Transferrin Receptor Antikörper (PE)

Produktnummer ABIN120510

Dieser Anti-Transferrin Receptor Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von Transferrin Receptor in FACS. Geeignet für Ratte.

Kurzübersicht für Transferrin Receptor Antikörper (PE) (ABIN120510)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: OX-26

Produktdetails anti-Transferrin Receptor Antikörper (PE)

Aufreinigung: Affinity chromatography on protein G

Immunogen: PHA activated rat lymphocytes. Spleen cells from immunised Balb/c mice were fused with cells of the NS1 mouse myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: RT/4 °C/-20 °C

Informationen zur Lagerung: Lyophilized: Store at 2-8 °C (preferably in a desiccator). Reconstituted: Aliquot and store at -20 °C.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71 / TFRC

Hintergrund: CD71 is a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimers, Parkinsons, Huntingtons and Multiple Sclerosis.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gen-ID: 10116

UniProt: Q99376

Pathways: Transition Metal Ion Homeostasis